What is Buphedrone?
This popular research chemical is a phenethylamine and cathinone chemical class stimulant. Buphedrone is also known as α-methylamino-butyrophenone or Phenylacetoethyl-methylamine, It is a beta-ketone and is related to the naturally occurring compounds, cathinone and cathine.
It is also related to methamphetamine, differing by the β-ketone substituent (at the beta carbon) and an ethyl group replacing the methyl group at the carbon alpha to the amine. The effects of iton test subjects have been compared to methamphetamine, with more euphoria and less physical stimulation noted in studies. It potentiates the release of dopamine from dopaminergic nerve terminals in the brain.
Substituted cathinone, like ethcathinone, are psychoactive compounds commonly used as recreational drugs.1,2 Some have amphetamine-like effects.3 Buphedrone (hydrochloride) is a substituted cathinone characterized by an ethyl group at the alpha position and an N-terminal methyl group. This compound has been identified in products sold as stimulants.2 Its biological and toxicological properties have not been evaluated. This product is intended for forensic applications.